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Previous Volume 344:1067-1078 April 5, 2001 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Electrocardiographically, atrial fibrillation is characterized by the presence of rapid, irregular, fibrillatory waves that vary in size, shape, and timing. This set of findings is usually associated with an irregular ventricular response, although regularization may occur in patients with complete heart block, an accelerated junctional or idioventricular rhythm, or a ventricular paced rhythm. In the past decade, we have gained a greater understanding of atrial fibrillation. Experimental studies have explored the mechanisms of the onset and maintenance of the arrhythmia; drugs have been tailored to specific cardiac ion channels; nonpharmacologic therapies have been introduced that are designed to control or . . . [Full Text of this Article]

Epidemiology

Histologic and Electrophysiologic Features

Hemodynamic Effects

Symptoms

Approach to the Patient with Atrial Fibrillation

Newly Diagnosed Atrial Fibrillation

Antiarrhythmic-Drug Therapy

Anticoagulation

Recurrent Paroxysmal Atrial Fibrillation

Antiarrhythmic-Drug Therapy

Persistent Atrial Fibrillation

Cardioversion

Long-Term Anticoagulation

Heart-Rate Control

Drug-Refractory Atrial Fibrillation

Ablation of the Atrioventricular Node and Implantation of a Pacemaker

Focal Ablation

The Maze Procedure

Pacemaker Therapy

Implantable Atrial Defibrillators

Conclusions

Source Information

From the Section of Cardiology, Boston Medical Center, Boston.

Address reprint requests to Dr. Falk at the Boston Medical Center, Section of Cardiology, 88 E. Newton St., Boston, MA 02118, or at rfalk@bu.edu.

References

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