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A correction has been published: N Engl J Med 2001;344(25):1956.

Review Article
Primary Care
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Volume 344:1145-1151 April 12, 2001 Number 15
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Epilepsy
Thomas R. Browne, M.D., and Gregory L. Holmes, M.D.

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Approximately 2 million persons in the United States have epilepsy,1,2 making the prevalence of this disorder similar to that of type 1 diabetes mellitus.3 Each year, 100,000 new cases of epilepsy are diagnosed in the United States.1,4 Both the prevalence and the incidence of epilepsy are dramatically higher among elderly persons than among those who are younger.1 Thus, many primary care physicians care for a substantial number of patients with epilepsy.

Evaluation

Diagnosis of a Seizure Disorder

The first step in the evaluation of a patient with possible epilepsy is to determine whether the patient does or does not have seizures. An incorrect diagnosis of a . . . [Full Text of this Article]

Diagnosis of the Underlying Cause

History

Physical Examination

Electroencephalographic Studies

Laboratory Tests and Neuroimaging

Diagnostic Formulation and Treatment Plan

Selection and Adjustment of Medications

Initial Toxicity

Toxic Effects during Long-Term Therapy

Inadequate Seizure Control

Discontinuing Therapy

When to Seek Neurologic Consultation

Refractory Status Epilepticus

Other Conditions

Routine Consultations


Source Information

From the Department of Neurology, Boston University School of Medicine, and the Neurology Service, Department of Veterans Affairs Boston Healthcare System (T.R.B.); and the Department of Neurology, Harvard Medical School and Children's Hospital (G.L.H.) — all in Boston.

Address reprint requests to Dr. Browne at the Department of Neurology, Boston University School of Medicine, 315 Albany St., C-314, Boston, MA 02118, or at tbrowne@bu.edu.

References


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