FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 344:1152-1158 April 12, 2001 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Presentation of Case

A 35-year-old woman was admitted to the hospital because of rapidly worsening renal failure.

Twelve years before admission, she had received a diagnosis of systemic lupus erythematosus, manifested by Raynaud's syndrome, thoracic and abdominal serositis, rash, and livedo reticularis. Two years later, the antiphospholipid-antibody syndrome was diagnosed; she had a miscarriage, a postpartum pulmonary embolus, ulcers on the fingertips, thrombocytopenia, and abnormal results on liver-function tests. More recently, she had had two successful pregnancies. Warfarin had been prescribed but was discontinued four months before admission because of inadequate compliance with blood testing, and daily aspirin was substituted. She also took . . . [Full Text of this Article]

Differential Diagnosis

Diagnosis of Systemic Lupus Erythematosus

Diagnosis of the Antiphospholipid-Antibody Syndrome

Cause of the Current Illness

Cause of Renal Failure

Conclusions

Clinical Diagnoses

Dr. Cecil H. Coggins's Diagnoses

Pathological Discussion

Thrombotic Microangiopathy

Systemic Lupus Erythematosus

Therapy and Outcome

Anatomical Diagnoses

References

This article has been cited by other articles:

• Karim, M Y, Alba, P, Tungekar, M F, Abbs, I C, Khamashta, M A, Hughes, G., Hunt, B J (2002). Hypertension as the presenting feature of the antiphospholipid syndrome. Lupus 11: 253-256 [Abstract]