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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 344:1232-1239 April 19, 2001 Number 16
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Case 12-2001— A 16-Year-Old Boy with an Altered Mental Status and Muscle Rigidity
Mark H. Libenson, and Jane M. Yang

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Presentation of Case

A 16-year-old boy was admitted to the hospital because of an altered mental and emotional status.

At an uncertain interval before admission, the patient began to have diarrhea. One week before admission, a sore throat and productive cough developed, with a vague sensation of fever, and he took an antihistamine. Although usually quiet, he became confused on noon of the day before admission and began to "talk nonsense." He was seen at another hospital, where he mentioned something that suggested an injection of illicit drugs. He spat at the nursing staff and used profane language. After haloperidol had been injected, . . . [Full Text of this Article]

Differential Diagnosis

Causes of an Acute Confusional State

Causes of Confusion with Episodic Muscle Rigidity

            Drugs

            Viral Encephalitis

            Epilepsy

            Tetanus

            Strychnine Poisoning

Clinical Diagnosis

Dr. Mark H. Libenson's Diagnosis

Pathological Discussion

Anatomical Diagnoses

References


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