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Correspondence
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Volume 344:1481-1482 May 10, 2001 Number 19
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Treatment of Parvovirus B19–Associated Polyarteritis Nodosa with Intravenous Immune Globulin

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To the Editor: We describe a patient who had polyarteritis nodosa associated with parvovirus B19 infection that regressed completely with intravenous immune globulin therapy.

A 33-year-old woman was seen because of asthenia, fever (temperature, 40°C), palpable purpura (Figure 1), intense myalgia, paresthesias along the median nerves and right peroneal nerve, and polyarthritis of the hand joints. Her younger son had had a febrile exanthem three weeks earlier.


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Figure 1. Cutaneous Purpuric, Palpable Nodules on the Lower Arm.

 
Enzyme-linked immunosorbent assay for serologic evidence of parvovirus B19, performed on day 4 of the illness, was positive for specific IgM and IgG . . . [Full Text of this Article]

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