To the Editor: We describe a patient infected with the humanimmunodeficiency virus (HIV) in whom diabetes mellitus developedin association with treatment with abacavir, a new nucleosidereverse-transcriptase inhibitor.
A 47-year-old homosexual man who was known to have had HIV infectionsince 1990 also had hypertension, which was treated with lisinopriland hydrochlorothiazide. He had no family history of diabetes.Antiretroviral therapy was begun in 1997. The patient had adversereactions to both zidovudine and stavudine and was then treatedwith didanosine, lamivudine, and hydroxyurea. Subsequently,his plasma HIV RNA load was less than 400 copies per milliliterand . . . [Full Text of this Article]
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