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Correspondence
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Volume 344:142-144 January 11, 2001 Number 2
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Abacavir and Diabetes

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To the Editor: We describe a patient infected with the human immunodeficiency virus (HIV) in whom diabetes mellitus developed in association with treatment with abacavir, a new nucleoside reverse-transcriptase inhibitor.

A 47-year-old homosexual man who was known to have had HIV infection since 1990 also had hypertension, which was treated with lisinopril and hydrochlorothiazide. He had no family history of diabetes. Antiretroviral therapy was begun in 1997. The patient had adverse reactions to both zidovudine and stavudine and was then treated with didanosine, lamivudine, and hydroxyurea. Subsequently, his plasma HIV RNA load was less than 400 copies per milliliter and . . . [Full Text of this Article]

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