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Previous Volume 344:1557-1558 May 17, 2001 Number 20 Next

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To the Editor: We question the scientific basis for several statements in Handelsman's recent review of our book, The Adonis Complex (Jan. 11 issue).¹ Handelsman dismisses anabolic-steroid–induced hypomanic syndrome (sometimes called "roid rage") as "street folklore" and "an excuse for bad behavior," a claim that contradicts the findings of three placebo-controlled, double-blind studies and numerous controlled field studies.^2,3 He also dismisses as "an unsubstantiated claim" our suggestion that there is a natural limit to the muscularity that lean men can attain without steroids, despite the fact that our hypothesis is based on a peer-reviewed study of 157 athletes⁴ that has . . . [Full Text of this Article]

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