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Correspondence
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Volume 344:1793-1796 June 7, 2001 Number 23
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Vaccinations and Multiple Sclerosis

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To the Editor: Ascherio et al. (Feb. 1 issue)1 report that they found no association between hepatitis B vaccination and the onset of multiple sclerosis. Vaccination was confirmed only in the respondents who said they had been vaccinated. Exclusions involved only the women with multiple sclerosis or the controls who had potentially been vaccinated, not those stating they had not been vaccinated. Similar rates of exclusion are cited for the women with multiple sclerosis and the controls, but with the wrong denominator, which should have referred to the positive cases and controls. Rather than exclude 35 percent of the women . . . [Full Text of this Article]

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