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Correspondence
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Volume 344:2030 June 28, 2001 Number 26
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Liver Biopsy

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To the Editor: Bravo et al. (Feb. 15 issue)1 list hemostatic contraindications to percutaneous liver biopsy. A prolonged bleeding time (>=10 minutes), in our opinion, has not been proved to predict a risk of biopsy-related bleeding. The evidence that supports the use of this test is based on clinical experience and expert opinion, not the results of controlled studies. The bleeding time is a poorly reproducible test, used for decades primarily because of the lack of a better substitute. Prospective studies in the literature have not convincingly shown that bleeding from a standardized cut in the skin reflects the . . . [Full Text of this Article]

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