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Figure 1. A 77-year-old man presented with a two-month history of fever, chills, and malaise. Three months earlier, he had undergone valve replacement for calcific aortic stenosis at another institution. Multiple subsequent blood cultures were positive for Candida albicans. Clinical signs of endocarditis (new murmurs, splenomegaly, Osler's nodes, and retinal lesions) were absent. Transesophageal echocardiography identified a mobile vegetation within the leaflets of the prosthetic valve that prolapsed into the ventricle during diastole. The patient was treated with amphotericin B and flucytosine for two weeks. At reoperation, the prosthetic valve (Panel A) contained a whitish vegetation (V) attached to . . . [Full Text of this Article] |