To the Editor: In the idiopathic nephrotic syndrome, includingfocal segmental glomerulosclerosis, a glomerular permeabilityfactor may be responsible for the development of proteinuriaand the recurrence of disease after renal transplantation.1,2Plasma from patients with active focal segmental glomerulosclerosiscan cause proteinuria in rats.3 The effect of a glomerular permeabilityfactor after transmission from one person to another is notknown. We report the transfer of an unknown glomerular permeabilityfactor from a mother with focal segmental glomerulosclerosisto her child.
The nephrotic syndrome developed in a 35-year-old woman (gravida5, para 3) in the 13th week of gestation . . . [Full Text of this Article]
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