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Previous Volume 344:530-531 February 15, 2001 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The article by Johnson et al. on the treatment of opioid dependence (Nov. 2 issue)¹ and the accompanying editorial by O'Connor² serve an important purpose in making physicians and, one hopes, the public more aware of the effectiveness of methadone maintenance for heroin dependence. It is discouraging, however, that the ineffectiveness of low-dose methadone therapy still has to be demonstrated. The effectiveness of methadone, at an average dose of 100 mg per day, was shown by Dole et al.³ more than 30 years ago and has been repeatedly confirmed since then, with some patients needing a dose . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Fiellin, D. A., O'Connor, P. G., Chawarski, M., Pakes, J. P., Pantalon, M. V., Schottenfeld, R. S. (2001). Methadone Maintenance in Primary Care: A Randomized Controlled Trial. JAMA 286: 1724-1731 [Abstract] [Full Text]