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Correspondence
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Volume 344:692-693 March 1, 2001 Number 9
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Treatment of Ciguatera Poisoning with Gabapentin

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To the Editor: Ciguatera poisoning from fish is caused by a neurotoxin (ciguatoxin) present in the dinoflagellate Gambierdiscus toxicus. The toxin is transferred through herbivorous reef fish to carnivorous tropical reef fish, which are consumed by humans. The toxin is lipid-soluble and is not inactivated by cooking, cold, or gastric juice. More than 200 species of fish have been implicated in causing ciguatera poisoning, the most common being grouper, red snapper, and barracuda. The primary endemic areas include the Caribbean and South Pacific islands, where the incidence is between 50 and 500 cases per 10,000 population.1,2

The symptoms of ciguatera . . . [Full Text of this Article]

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