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Previous Volume 344:695-696 March 1, 2001 Number 9 Next

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Third edition. Edited by Robert Ader, David L. Felten, and Nicholas Cohen. 1583 pp. in two volumes, illustrated. San Diego, Calif., Academic Press, 2001. $299.95. ISBN 0-12-044314-7.

During the past two decades, there have been major efforts to understand the influence of the nervous system on immune and inflammatory responses. As a result, it has become clear that the immune system communicates with the neuroendocrine system and that imbalances in the neuroendocrine–immune circuitry are relevant to host defenses. This knowledge is the basis of the scientific discipline called psychoneuroimmunology.

The first edition of Psychoneuroimmunology was published in 1981 and helped to establish the new discipline. In addition to covering the scant amount of research on the subject that was available at that time, it contained a seminal . . . [Full Text of this Article]

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