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Correspondence
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Volume 345:66 July 5, 2001 Number 1
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Lack of Effect of Induction of Hypothermia after Acute Brain Injury

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To the Editor: The study by Clifton et al. (Feb. 22 issue)1 has two shortcomings. First, brain temperature was not monitored. Second, the types of injuries were neither described nor analyzed. Hypothermia might be beneficial in patients with specific types or areas of injury in the brain — for example, areas of edema or areas of focal contusions. In such injured but potentially viable areas, cerebral perfusion may be diminished or even absent. Cooling the blood in the systemic circulation to the predetermined level of 33°C (as measured by bladder temperature), as in the study by Clifton et al., may . . . [Full Text of this Article]

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