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Previous Volume 345:71-72 July 5, 2001 Number 1 Next

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Second edition. Edited by Douglas A. Drossman, with Enrico Corazziari, Nicholas H. Talley, W. Grant Thompson, and William E. Whitehead. 764 pp., illustrated. McLean, Va., Degnon, 2000. $99.50. ISBN 0-96568-371-0.

It has been said that only 10 percent of medical illnesses can be attributed to specific diseases; even patients with cancer vary greatly in their responses to it. According to the traditional biomedical concept of disease, the functional gastrointestinal disorders — irritable bowel syndrome, functional dyspepsia, and others — are "nonentities," with no clear-cut structural, biochemical, or physiologic basis. Yet these disorders account for a considerable proportion of visits to gastroenterologists and primary care physicians. Elucidating the mechanisms of functional bowel disease and developing effective treatments are therefore major challenges.

Rome II: The Functional Gastrointestinal Disorders is the second edition . . . [Full Text of this Article]

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