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Correspondence
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Volume 345:769-770 September 6, 2001 Number 10
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Spontaneous Intracerebral Hemorrhage

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To the Editor: Qureshi et al., in their review of spontaneous intracerebral hemorrhage (May 10 issue),1 point out that a low Glasgow Coma Scale score, a hematoma of large volume, and the presence of ventricular blood on the initial computed tomographic (CT) scan of the brain consistently predict a high mortality rate. Genetic determinants of outcome after acute brain injury may provide future opportunities for successful medical intervention. It has been well established that patients carrying the {epsilon}4 allele of the apolipoprotein E gene have a poorer outcome after acute head injury than those who do not carry {epsilon}4.2 . . . [Full Text of this Article]

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