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Previous Volume 345:1206-1207 October 18, 2001 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The genomic sequences of more than 30 bacterial species, including virtually all important human pathogens, have been deciphered. The pneumococcus, discovered in 1880 virtually simultaneously by Pasteur in France and Sternberg in the United States and used extensively in the 20th century to probe fundamental questions of life,¹ was only recently added to this list.² What can be learned from the description of yet another bacterial genome — in this case the 2,160,837 base pairs of Streptococcus pneumoniae serotype 4, which make up some 2236 genes? Several unexpected discoveries resulted from the mining of the genomic sequence of this virulent . . . [Full Text of this Article]

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• Jado, I., Lopez, R., Garcia, E., Fenoll, A., Casal, J., Garcia, P., on behalf of the Spanish Pneumococcal Infection St, (2003). Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model. J Antimicrob Chemother 52: 967-973 [Abstract] [Full Text]  
• Reid, S. D., Green, N. M., Sylva, G. L., Voyich, J. M., Stenseth, E. T., DeLeo, F. R., Palzkill, T., Low, D. E., Hill, H. R., Musser, J. M. (2002). Postgenomic Analysis of Four Novel Antigens of Group A Streptococcus: Growth Phase-Dependent Gene Transcription and Human Serologic Response. J. Bacteriol. 184: 6316-6324 [Abstract] [Full Text]