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Previous Volume 345:1213-1214 October 18, 2001 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: PC-SPES is a commercially available nutritional supplement containing eight herbs that is used by many patients with prostate cancer. It has potent estrogenic activity and substantial antineoplastic effects in patients with prostate cancer.^1,2 We describe a patient with profound bleeding diathesis after one month of unsupervised use of this compound.

A 62-year-old man with hormone-refractory prostate cancer and nodal metastases (stage D1 disease) presented to the emergency department after an episode of syncope. This episode had been preceded by one day of epistaxis, abdominal pain, hematuria, and the passage of maroon stools. The patient denied a family . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Kosty, M. P. (2004). PC-SPES: Hope or Hype?. JCO 22: 3657-3659 [Full Text]  
• Weiger, W. A., Smith, M., Boon, H., Richardson, M. A., Kaptchuk, T. J., Eisenberg, D. M. (2002). Advising Patients Who Seek Complementary and Alternative Medical Therapies for Cancer. ANN INTERN MED 137: 889-903 [Abstract] [Full Text]  
• White, J. (2002). PC-SPES-A Lesson for Future Dietary Supplement Research. JNCI J Natl Cancer Inst 94: 1261-1262 [Full Text]  
• Sovak, M., Seligson, A. L., Konas, M., Hajduch, M., Dolezal, M., Machala, M., Nagourney, R. (2002). Herbal Composition PC-SPES for Management of Prostate Cancer: Identification of Active Principles. JNCI J Natl Cancer Inst 94: 1275-1280 [Abstract] [Full Text]