There has been considerable controversy about the ethics ofclinical trials that are sponsored or conducted by groups inindustrialized countries but carried out in developing countries.1,2,3,4,5,6,7,8The National Bioethics Advisory Commission, of which we serveas chairman and executive director, respectively, has recentlyaddressed these and related issues.9 International collaborativeresearch covers a broad spectrum of methods, topics, and researchstrategies. In this essay, we discuss ethical issues in thedesign and conduct of clinical trials in developing countries.In particular, we focus on phase 3 and other drug trials that,if successful, can lead to the use of . . . [Full Text of this Article]
Exporting Ethical Standards
Specific Ethical Issues
The Process of Informed Consent
Research Design and Ethics Review
Post-Trial Benefits
Conclusions
References
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