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Previous Volume 345:148-149 July 12, 2001 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: McJunkin et al. (March 15 issue)¹ report that in patients with La Crosse encephalitis who have clinical deterioration, it follows the development of hyponatremia. This observation underscores the danger of administering hypotonic maintenance fluids in children. The hyponatremia in these patients may have been iatrogenic, since they presented with normal serum sodium levels.

The administration of hypotonic fluids in children can be lethal² for many reasons. Many hospitalized children have impaired excretion of free water as a result of either the syndrome of inappropriate antidiuretic hormone secretion due to pulmonary or central nervous system disease or physiologic . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Hoorn, E. J., Geary, D., Robb, M., Halperin, M. L., Bohn, D. (2004). Acute Hyponatremia Related to Intravenous Fluid Administration in Hospitalized Children: An Observational Study. Pediatrics 113: 1279-1284 [Abstract] [Full Text]  
• Moritz, M. L., Ayus, J. C. (2004). Hospital-Acquired Hyponatremia: Why Are There Still Deaths?. Pediatrics 113: 1395-1396 [Full Text]  
• Moritz, M. L., Ayus, J. C. (2003). The pathophysiology and treatment of hyponatraemic encephalopathy: an update. Nephrol Dial Transplant 18: 2486-2491 [Full Text]  
• Playfor, S (2003). Fatal iatrogenic hyponatraemia. Arch. Dis. Child. 88: 646-647 [Full Text]  
• Moritz, M. L., Ayus, J. C. (2003). Prevention of Hospital-Acquired Hyponatremia: A Case for Using Isotonic Saline. Pediatrics 111: 227-230 [Abstract] [Full Text]