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Editorial
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Volume 345:1493-1495 November 15, 2001 Number 20
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Oral Anticoagulant Therapy for the Prevention of Stroke

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 by Mohr, J.P.
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This year in the United States, 450,000 people will have a first ischemic stroke.1,2,3 For these patients (including those receiving thrombolytic therapy), the primary therapeutic goals will be rehabilitation and the prevention of another stroke. The optimal preventive therapy should be determined on the basis of the results of randomized, controlled trials. Trials have demonstrated that selected patients with an ischemic stroke in the territory of a stenotic carotid artery have a lower risk of recurrence if they are treated with carotid endarterectomy, rather than with antiplatelet therapy.4 Patients with atrial fibrillation have a lower risk of recurrence with oral . . . [Full Text of this Article]

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