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Previous Volume 345:1537-1541 November 22, 2001 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Editorial by Elias, S. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

During in vitro fertilization, morphologically normal embryos often fail to implant. The implantation rate, defined as the ratio of the number of fetal hearts detected to the number of cleavage-stage embryos transferred, is at best approximately 15 to 20 percent, even in experienced centers.¹ Early human embryos have a high frequency of aneuploidy, as determined by fluorescence in situ hybridization. Analysis by this method of three to six chromosomes from every cell in early human embryos generated by in vitro fertilization shows that 50 to 70 percent of these embryos have chromosomal errors, including aneuploidy, polyploidy, and mosaicism.^2,3,4 This rate . . . [Full Text of this Article]

Methods

Results

Discussion

Source Information

From Melbourne IVF, East Melbourne (L.W., J.M., D.E.), and Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville (R.W., L.V.) — both in Victoria, Australia.

Address reprint requests to Dr. Wilton at Melbourne IVF, 320 Victoria Parade, East Melbourne 3002, Victoria, Australia, or at lwilton@mivf.com.au.

References

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