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Previous Volume 345:1569-1571 November 22, 2001 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Currently, the most common techniques for prenatal diagnosis are amniocentesis, performed between 14 and 22 weeks' gestation, and chorionic-villus sampling, performed between 14 and 20 weeks' gestation. Although generally regarded as safe, both of these techniques lead to fetal loss in 0.5 to 1.0 percent of women who undergo them.^1,2 Preimplantation genetic diagnosis was initially developed as an extension of prenatal diagnosis. Its original purpose was to identify embryos affected by single-gene disorders such as cystic fibrosis.

In contrast to amniocentesis and chorionic-villus sampling, techniques for preimplantation genetic diagnosis are performed before the establishment of a pregnancy, thereby sparing women . . . [Full Text of this Article]

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