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Previous Volume 345:1748-1757 December 13, 2001 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Periodic fever is defined as recurrences of fever that last from a few days to a few weeks, separated by symptom-free intervals of variable duration. This pattern of fever can be caused by recurrent infections or neoplastic disorders but also by noninfectious inflammatory disorders.¹ It is important to review the medical history carefully in patients with recurrent febrile attacks. Patients with periodic fever that persists for more than two years rarely have infections or malignant disorders. Attacks with a predictable course and a similar set of symptoms, along with a family history of such attacks, may suggest the presence of . . . [Full Text of this Article]

Familial Mediterranean Fever

Clinical Features

Genetic and Epidemiologic Features

Laboratory Findings

Pathogenesis and Molecular Genetic Features

Treatment

Prognosis

Diagnostic Strategy

Hyper-IgD Syndrome

Clinical Features

Genetic and Epidemiologic Features

Laboratory Findings

Pathogenesis and Molecular Genetic Features

Treatment

Prognosis

Diagnostic Strategy

TNF-Receptor–Associated Periodic Syndrome

Clinical Features

Genetic and Epidemiologic Features

Laboratory Findings

Pathogenesis and Molecular Genetic Features

Treatment

Prognosis

Diagnostic Strategy

Further Considerations

Source Information

From the Department of Medicine, Division of Gastroenterology and Hepatology (J.P.H.D.), and the Division of General Internal Medicine (J.W.M.M.), University Medical Center St. Radboud, Nijmegen, the Netherlands.

Address reprint requests to Dr. Drenth at the Department of Medicine, Division of Gastroenterology and Hepatology, University Medical Center St. Radboud, P.O. Box 9101, 6500 HB Nijmegen, the Netherlands, or at joostphdrenth@cs.com.

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