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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 345:1758-1765 December 13, 2001 Number 24
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Case 38-2001— A 51-Year-Old Woman with Lung Cancer and Neuropsychiatric Abnormalities
Anthony A. Amato, M.D., and Matthew P. Anderson, M.D., Ph.D.

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Presentation of Case

A 51-year-old woman was admitted to the hospital because of paresthesias, ataxic gait, and hallucinations.

The patient had been well until 9 or 10 months earlier, when tingling and numbness developed in all her fingers, with weakness of her hands and a burning sensation in her feet. A tentative diagnosis of bilateral carpal tunnel syndrome was made, but no neurophysiological studies were undertaken. Six months before admission, "asthmatic bronchitis" developed, with a cough that became productive, accompanied by mild hemoptysis. At about the same time, she began to have difficulty finding words and remembering the names of family members.

Five . . . [Full Text of this Article]

Differential Diagnosis

Peripheral Neuropathy and Malignant Tumors

Sensory Neuronopathies

Clinical Diagnoses

Dr. Anthony A. Amato's Diagnosis

Pathological Discussion

Anatomical Diagnoses

References


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