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Previous Volume 345:1844-1846 December 20, 2001 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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"Take two aspirin and call me in the morning"? Clinical decision making is no longer so straightforward. Millions of patients take analgesic and antiinflammatory medications regularly. The reasons are simple: these drugs are effective in relieving pain and inflammation,¹ and aspirin provides protection from cardiovascular thrombosis.^2,3 Osteoarthritis and other painful chronic conditions occur in a population of patients who often have coexisting medical conditions, including conditions associated with an increased risk of cardiovascular disease. Thus, aspirin is frequently prescribed for patients taking other analgesic and antiinflammatory agents. Since the mechanism of action of all these drugs is the inhibition of . . . [Full Text of this Article]

References

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• Lippi, G, Franchini, M, Guidi, G C, Kean, W F (2006). Non-steroidal anti-inflammatory drugs in athletes * Commentary. Br. J. Sports. Med. 40: 661-663 [Full Text]  
• Dai, W., Kloner, R. A. (2003). Effects of Acetaminophen on Myocardial Infarct Size in Rats. J CARDIOVASC PHARMACOL THER 8: 277-284 [Abstract]  
• Burke, J., Kraft, W. K., Greenberg, H. E., Gleave, M., Pitari, G. M., VanBuren, S., Wagner, J. A., Waldman, S. A. (2003). Relationship of Arachidonic Acid Concentration to Cyclooxygenase-Dependent Human Platelet Aggregation. J Clin Pharmacol 43: 983-989 [Abstract] [Full Text]