To the Editor: Extramedullary plasmacytomas occur either assolitary (primary) tumors or as secondary manifestations ofmultiple myeloma. Involvement of the orbit is very rare in bothentities.1 Patients characteristically present with exophthalmos,increased tearing, blurred vision, or diplopia.2 Although neurologicsymptoms in multiple myeloma can be due to hyperviscosity orhypercalcemia, only 50 cases of multiple myeloma involving thecentral nervous system have been documented, and most of themwere of meningeal origin.3 We describe a patient with multiplemyeloma and secondary orbital, intracranial, and cutaneous plasmacytomas.
A 42-year-old man was referred with a histologically confirmedretrobulbar plasmacytoma. He . . . [Full Text of this Article]
References
This article has been cited by other articles:
Montalban, C., Martin-Aresti, J., Patier, J. L., Millan, J. M.-S., Cosio, M. G.
(2005). Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 3. Intracranial Plasmacytoma With Cranial Nerve Neuropathy in Multiple Myeloma. JCO
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Requena, L., Kutzner, H., Palmedo, G., Calonje, E., Requena, C., Perez, G., Pastor, M. A., Sangueza, O. P.
(2003). Cutaneous Involvement in Multiple Myeloma: A Clinicopathologic, Immunohistochemical, and Cytogenetic Study of 8 Cases. Arch Dermatol
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