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Two decades ago, it would have been unthinkable that the devastating effects of ischemic stroke would ever be completely reversible, but with thrombolysis this is now a reality. Unfortunately, the therapeutic window remains impracticably narrow (the three-hour barrier has not yet been effectively overcome), and the treatment is very expensive, so that even in the developed world successful thrombolysis is only possible in a tiny minority of patients.
Stroke is now the second most common cause of death globally, with most cases occurring in the developing world, according to statistics from the World Health Organization. Unlike the impracticality of treating
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