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Previous Volume 345:351-358 August 2, 2001 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The deaths of several celebrities in recent years in association with the nontherapeutic use of cocaine have focused widespread attention on the problem of cocaine abuse. In 1999, an estimated 25 million Americans admitted that they had used cocaine at least once; 3.7 million had used it within the previous year; and 1.5 million were current users. During the same year, cocaine was mentioned in 30 percent of all drug-related visits to emergency departments.¹ Cocaine is the most commonly used illicit drug among subjects seeking care in hospital emergency departments or drug-treatment centers. In addition, it is the most frequent . . . [Full Text of this Article]

Pharmacology and Mechanisms of Action

Cocaine-Related Myocardial Ischemia and Infarction

Cocaine, Cigarette Smoking, and Alcohol Use

Cocaine-Induced Myocardial Dysfunction

Cocaine-Induced Dysrhythmias

Endocarditis

Aortic Dissection

Conclusions

Source Information

From the Cardiovascular Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.

Address reprint requests to Dr. Hillis at the Department of Internal Medicine, Room CS7.102, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9047.

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