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A 29-year-old woman with no previous pregnancies presented with a nine-week history of amenorrhea. The serum levels of the beta subunit of chorionic gonadotropin (peak, 117,000 U per liter) and ultrasonographic findings were indicative of a molar pregnancy. Dilation and curettage was performed; 10 weeks later, serum levels of the beta subunit of chorionic gonadotropin were undetectable and the patient was well. Gross analysis of the uterine contents demonstrated enlarged, edematous villi with a classic grape-like appearance (Panel A). No fetal parts were present. Histopathological analysis showed markedly edematous chorionic villi with circumferential, haphazard proliferation of trophoblasts on the villous . . . [Full Text of this Article] |