The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Perspective
Volume 346:722 March 7, 2002 Number 10
NextNext

Attacking the Pneumococcus — A Hundred Years' War

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
-Related Article
 by Davidson, R.
-PubMed Citation
The battle with pneumococcus over the past century is reminiscent of the Hundred Years' War, the struggle between England and France that was interrupted by truces and stalemates. Streptococcus pneumoniae was isolated by Pasteur in 1881 and was soon recognized as the commonest cause of lobar pneumonia. When Dochez and Gillespie divided S. pneumoniae into 4 types (there are currently 90) on the basis of capsular antigens, the fatality rate associated with untreated pneumococcal pneumonia was 33 percent. By 1936, the use of type-specific antiserum reduced mortality to about 18 percent.

Sulfonamides were introduced in the 1930s for the treatment . . . [Full Text of this Article]


This article has been cited by other articles:



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.