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Volume 346:773-775 March 7, 2002 Number 10
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Ooplasmic Transfer — Proceed with Care

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This is an exciting time in the field of human gamete biology, with the real possibility that advances will result in both wider application and an increased efficiency of current techniques of in vitro fertilization. Somatic-cell nuclei can be transferred to reconstructed oocytes and reprogrammed to produce stem cells. Furthermore, under certain circumstances, the somatic-cell nuclei undergo a reduction division, with exclusion of one of the two haploid sets of chromosomes, a process called haploidization.1,2 Although this latter observation offers the possibility that parenthood could be extended to men and women who have no gametes or germ cells, so far . . . [Full Text of this Article]

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Related Letters:

Ooplasmic Transfer
Robertson J. A.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:147-148, Jul 11, 2002. Correspondence

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