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Correspondence
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Volume 346:867-869 March 14, 2002 Number 11
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Nosocomial Spread of Linezolid-Resistant, Vancomycin-Resistant Enterococcus faecium

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To the Editor: Vancomycin-resistant enterococci have become important nosocomial pathogens in the United States. Since November 1995, rectal swabs for surveillance for vancomycin-resistant enterococci have been collected twice weekly from adult patients admitted to the liver, kidney, and pancreas transplantation unit at our institution.1 Recently, linezolid-resistant, vancomycin-resistant Enterococcus faecium was isolated from seven patients at our institution. All isolates carried the vanA gene and were resistant to linezolid (minimal inhibitory concentration [MIC], 16 µg per milliliter), ampicillin, penicillin, gentamicin, streptomycin, and vancomycin and were susceptible to quinupristin–dalfopristin and the investigational agents oritavancin (MIC, 1 µg per milliliter) and tigecycline (MIC, . . . [Full Text of this Article]

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