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Previous Volume 346:947-948 March 21, 2002 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Functional dyspepsia is a common and distressing chronic digestive disorder of unknown cause.^1,2 We examined the effect of treatment of functional dyspepsia with capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), a component of red-pepper (Capsicum annum) powder. Capsaicin selectively impairs the activity of nociceptive C fibers carrying pain sensations to the central nervous system³ and has been shown to relieve pain of cutaneous and mucosal origin.⁴

After the exclusion of patients with gastroesophageal reflux and irritable bowel syndrome, we monitored 30 patients with functional dyspepsia² for two weeks while they were receiving no medications. Fifteen patients were randomly . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Schmidt, B, Hammer, J, Holzer, P, Hammer, H F (2004). Chemical nociception in the jejunum induced by capsaicin. Gut 53: 1109-1116 [Abstract] [Full Text]