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Correspondence
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Volume 346:1023-1025 March 28, 2002 Number 13
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Left Ventricular Assist Device

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To the Editor: Rose et al. (Nov. 15 issue)1 performed a seminal trial of the use of a left ventricular assist device for end-stage heart failure. However, to gauge the full extent of the effect of invasive therapy with a left ventricular assist device on the health-related quality of life, missing data must be accounted for (i.e., subjects who died between administrations of the questionnaires measuring health-related quality of life or who are alive but did not participate in serial evaluations).2 For example, among other statistical techniques, the investigators could assign the "worst possible score" to those who died or, . . . [Full Text of this Article]

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