This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the author's clinicalrecommendations.
A 68-year-old former heavy smoker with a history of chronicobstructive pulmonary disease (COPD) presents to the emergencyroom with a two-day history of worsened dyspnea and increasedpurulence and volume of phlegm. Chest radiography shows hyperinflationand no acute infiltrates. Measurement of arterial blood gaseswhile the patient is breathing room air shows acute respiratoryacidosis. How should this patient be . . . [Full Text of this Article]
The Clinical Problem
Strategies and Evidence
Overview
Diagnostic Assessment
Oxygen
Bronchodilators
Antibiotics
Corticosteroids
Noninvasive Positive-Pressure Ventilation
Areas of Uncertainty
Guidelines
Summary and Recommendations
Source Information
From the Division of Medicine and the Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland.
Address reprint requests to Dr. Stoller at the Department of Pulmonary and Critical Care Medicine, A90, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, or at stollej@ccf.org.
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