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Clinical Practice
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Volume 346:988-994 March 28, 2002 Number 13
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Acute Exacerbations of Chronic Obstructive Pulmonary Disease
James K. Stoller, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 68-year-old former heavy smoker with a history of chronic obstructive pulmonary disease (COPD) presents to the emergency room with a two-day history of worsened dyspnea and increased purulence and volume of phlegm. Chest radiography shows hyperinflation and no acute infiltrates. Measurement of arterial blood gases while the patient is breathing room air shows acute respiratory acidosis. How should this patient be . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Overview

Diagnostic Assessment

Oxygen

Bronchodilators

Antibiotics

Corticosteroids

Noninvasive Positive-Pressure Ventilation

Areas of Uncertainty

Guidelines

Summary and Recommendations


Source Information

From the Division of Medicine and the Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland.

Address reprint requests to Dr. Stoller at the Department of Pulmonary and Critical Care Medicine, A90, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, or at stollej@ccf.org.

References


Related Letters:

Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Barr R. G., Stoller J. K.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:1533-1534, Nov 7, 2002. Correspondence

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