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Previous Volume 346:1096-1097 April 4, 2002 Number 14 Next

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To the Editor: In their Clinical Practice article (Dec. 6 issue),¹ Fleisher and Eagle state that the effect of aspirin on perioperative complications has not been studied sufficiently and, therefore, recommendations cannot be made. However, aspirin has gained widespread use in the primary and secondary prevention of cardiovascular disease.² Therefore, the question of whether perioperative continuation of aspirin improves cardiovascular outcome is of high clinical relevance.

Historically, aspirin was discontinued one week before most surgical interventions to reduce the risk of bleeding. However, Tuman et al. demonstrated that continuation of aspirin treatment in patients undergoing cardiac surgery is not associated . . . [Full Text of this Article]

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