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Previous Volume 346:1300-1308 April 25, 2002 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The last case of endemic smallpox occurred in Somalia in 1977, and eradication of the disease was declared in 1980. With no natural reservoir, variola virus, which causes smallpox, has existed only in laboratories; indeed, the last case of smallpox was due to infection acquired in a laboratory in the United Kingdom in 1978. During the global program of smallpox eradication, the World Health Organization (WHO) made concerted efforts to decrease the number of laboratories retaining variola virus. On the basis of contacts with all countries and a total of 823 microbiology institutions, 76 such laboratories had been identified by . . . [Full Text of this Article]

Virology

Pathogenesis

Clinical Manifestations

Diagnosis

Emergency Reporting

Epidemiology

Treatment

Prevention

Research Issues

Source Information

From the Fogarty International Center, National Institutes of Health, Bethesda, Md. (J.G.B.); and Johns Hopkins University, Baltimore (D.A.H.).

This article was published at www.nejm.org on March 28, 2002.

Address reprint requests to Dr. Breman at the Fogarty International Center, National Institutes of Health, 16 Center Dr., MSC 6705, Bldg. 16, Rm. 214, Bethesda, MD 20892, or at jbreman@nih.gov.

References

Related Letters:

Diagnosis of Smallpox
Regan T. D., Norton S. A.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:690-691, Aug 29, 2002. Correspondence

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