To the Editor: Casadevall et al. (Feb. 14 issue)1 reported 13cases of pure red-cell aplasia and antierythropoietin antibodiesin European patients who received recombinant erythropoietin(epoetin). Data submitted to the Food and Drug Administrationsuggest important differences among brands of epoetin with regardto recent increases in reports of pure red-cell aplasia.
Epogen, Procrit, and Eprex are brands of epoetin licensed inthe United States. Epogen and Procrit are identical formulationsof the same active ingredient (epoetin) distributed only inthe United States. Eprex is a different product, which is distributedonly outside the United States. For all biologic . . . [Full Text of this Article]
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