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Correction to Seufert et al., N Engl J Med 345(26):1883-1888 December 27, 2001.

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Volume 346:1748-1749 May 30, 2002 Number 22
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Octreotide for Tumor-Induced Osteomalacia

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 by Seufert, J.
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 by Seufert, J.
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To the Editor: Seufert et al. (Dec. 27 issue)1 describe a man with tumor-induced (oncogenic) osteomalacia, in which the subcutaneous administration of octreotide abolished renal tubular phosphate wasting. The authors suggest that in patients who cannot undergo surgery, phosphate wasting may be relieved by treatment with somatostatin analogues, provided that the tumor expresses somatostatin receptors. We believe that this statement is a misleading generalization. We observed a case of oncogenic osteomalacia in which total-body octreotide scintigraphy detected the tumor. We therefore intravenously administered octreotide at a dose of 600 µg per day for six days — a dose in the . . . [Full Text of this Article]

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