An estimated 16.4 million women worldwide are living with humanimmunodeficiency virus (HIV) infection; 600,000 children areinfected annually, most of them by mother-to-child transmission.1Interventions designed to reduce perinatal transmission of HIVin the developing world have been described elsewhere.2 Thisarticle focuses on the management of HIV infection in pregnantwomen in developed countries where antiretroviral therapy, scheduledcesarean delivery, and alternatives to breast-feeding are available(Table 1). Standards of care for HIV change rapidly, and up-to-daterecommendations are available on the Web (e.g., at http://www.hivatis.org).Clinicians who care for HIV-infected women of reproductive . . . [Full Text of this Article]
Interaction between HIV Infection and Pregnancy
Data on Antiretroviral Drugs during Pregnancy
Nucleoside Reverse-Transcriptase Inhibitors
Nonnucleoside Reverse-Transcriptase Inhibitors
Protease Inhibitors
Indications for Antiretroviral Therapy during Pregnancy
Drug Resistance
Ongoing Therapy
Mode of Delivery
Prevention and Treatment of Opportunistic Infections during Pregnancy
Other Aspects of Care for HIV-Infected Pregnant Women
Antepartum Care
Intrapartum Care
Postpartum Care
Source Information
From the Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research on Mothers and Children, National Institute of Child Health and Human Development, Bethesda, Md.
Address reprint requests to Dr. Watts at the Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of Child Health and Human Development, 6100 Executive Blvd., Rm. 4B11, Bethesda, MD 20892, or at hw59i@nih.gov.
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