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A correction has been published: N Engl J Med 2002;347(13):1050.

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Volume 346:2095 June 27, 2002 Number 26
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Seizure Associated with the Use of Visicol for Colonoscopy

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To the Editor: Visicol (InKine Pharmaceutical), which contains 1.5 g of sodium phosphate per tablet, is a bowel evacuant for colonoscopy that was approved by the Food and Drug Administration (FDA) in September 2000. Its proposed mechanism of action is an osmotic effect. Twenty tablets are taken the evening before the colonoscopy (three tablets with at least 8 oz of clear liquids every 15 minutes [the last dose being two tablets]) and again the next morning.1 From April to July 2001, four reports of tonic–clonic seizure associated with the administration of Visicol were received by the FDA MedWatch system (. . . [Full Text of this Article]


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