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Previous Volume 346:206-208 January 17, 2002 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The results of the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study (Aug. 16 issue)¹ suggest that the addition of clopidogrel to aspirin is beneficial for patients who have acute coronary syndromes without elevation of the ST segment. The inclusion criteria were changed after the first 3000 patients had been recruited. This change in the entry criteria during the course of recruitment means that the analysis of the results could be interpreted as a meta-analysis of two separate studies, rather than a single study. If one takes this view, the findings necessarily carry less weight.

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References

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