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Book Review
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Volume 346:299 January 24, 2002 Number 4
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Human Trials: Scientists, Investors, and Patients in the Quest for a Cure

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By Susan Quinn. 260 pp. Cambridge, Mass., Perseus Publishing, 2001. $26. ISBN 0-7382-0182-0.

This book is not a mystery story, so I can tell you the ending: 56 percent of patients with multiple sclerosis had a response to placebo in a double-blind, randomized trial, and 56 percent had a response to oral myelin (Myloral). Did the treatment fail, or was it killed by an unusual "placebo effect"? Susan Quinn unfolds the stories of scientists, investors, and patients, all of whom were seeking success. If you are unfamiliar with the literature on multiple sclerosis, the book does read like a mystery that is not solved until the last chapter. The story follows what is . . . [Full Text of this Article]




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