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Clinical Practice
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Volume 346:334-339 January 31, 2002 Number 5
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Antibiotic-Associated Diarrhea
John G. Bartlett, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 53-year-old woman reports severe watery diarrhea with cramps. She is in her 7th day of a 10-day course of cefixime, prescribed for bronchitis. How should she be evaluated and treated?

The Clinical Problem

Antibiotic-associated diarrhea is defined as otherwise unexplained diarrhea that occurs in association with the administration of antibiotics. The frequency of this complication varies among antibacterial agents. Diarrhea occurs in approximately 5 . . . [Full Text of this Article]

Strategies and Evidence

Mechanisms Other Than C. difficile Infection

Diarrhea Associated with C. difficile Infection

            Risk Factors

            Diagnostic Tests

            Treatment

            Relapsing Infection

            Epidemics

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Department of Medicine, Johns Hopkins School of Medicine, Baltimore.

Address reprint requests to Dr. Bartlett at the Department of Medicine, Johns Hopkins University School of Medicine, 1830 E. Monument St., Rm. 439, Baltimore, MD 21287-0003, or at jb@jhmi.edu.

References


Related Letters:

Antibiotic-Associated Diarrhea
Periman P., Bartlett J. G.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:145, Jul 11, 2002. Correspondence

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