In this issue of the Journal, the reported results of two randomizedclinical trials, one in Australia1 and the other in Europe,2showed a neurologic benefit of mild therapeutic hypothermia(33°C in the first study and 32°C to 34°C in thesecond) in survivors of out-of-hospital cardiac arrest.3 Inthe Australian study, which involved a total of 77 patientswho remained comatose after the restoration of spontaneous circulation,49 percent of those treated with hypothermia were dischargedhome or to a rehabilitation facility, as compared with 26 percentof those not treated with hypothermia (P=0.046).1 There wereno significant differences . . . [Full Text of this Article]
References
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Therapeutic Hypothermia after Cardiac Arrest
Darby J. M., Padosch S. A., Kern K. B., Böttiger B. W., Polderman K. H., Girbes A. R.J., Holzer M., the Hypothermia after Cardiac Arrest Study Group , Bernard S. A., Buist M. D., Safar P., Kochanek P. M.
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N Engl J Med 2002;
347:63-65, Jul 4, 2002.
Correspondence
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