To the Editor: Pulmonary alveolar microlithiasis is a rare diseaseof unknown pathogenesis, characterized by widespread laminatedcalcispherites in alveolar spaces in the absence of any knowndisorder of calcium metabolism.1 It usually occurs in a sporadicform, but an autosomal recessive form has been described, especiallyin patients from the Mediterranean countries.2,3,4,5 We reporton two initially asymptomatic, nonsmoking siblings: a 38-year-oldwoman and her 41-year-old brother, both of whom were given adiagnosis of pulmonary alveolar microlithiasis. In both patients,chest x-ray films and a computed tomographic scan (Figure 1)showed diffusely scattered, bilateral, micronodular areas . . . [Full Text of this Article]
Gasparetto, E L, Tazoniero, P, Escuissato, D L, Marchiori, E, Frare e Silva, R L, Sakamoto, D
(2004). Pulmonary alveolar microlithiasis presenting with crazy-paving pattern on high resolution CT. Br. J. Radiol.
77: 974-976
[Abstract][Full Text]
Yesner, R., Barbolini, G., Rossi, G.
(2003). Pulmonary Alveolar Microlithiasis Revisited. NEJM
348: 84-85
[Full Text]