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Previous Volume 347:817-823 September 12, 2002 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 30-year-old man reports a two-year history of heroin use. For the past year, he has been using intranasal heroin every day. He has undergone detoxification twice at a local opioid treatment program but began using heroin within two days after discharge each time. He has heard of methadone but fears that he will lose his business if he is recognized attending . . . [Full Text of this Article]

The Clinical Problem

Diagnosis

Epidemiology of Opioid Dependence

Opioid Treatment Programs as Compared with Office-Based Care

Federal Initiatives Regarding Office-Based Treatment

Strategies and Evidence

Detoxification

Office-Based Detoxification

Opioid-Agonist Maintenance Therapy

Office-Based Opioid-Agonist Maintenance Therapy

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.

Address reprint requests to Dr. Fiellin at the Department of Internal Medicine, Yale University School of Medicine, 333 Cedar St., P.O. Box 208025, New Haven, CT 06520-8025, or at david.fiellin@yale.edu.

Related Letters:

Office-Based Treatment of Opioid-Dependent Patients
Ferner R. E., Daniels A. M., Fiellin D. A., O'Connor P. G.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:81-82, Jan 2, 2003. Correspondence

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