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Previous Volume 347:843-845 September 12, 2002 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Addictions are relapsing, remitting lifelong illnesses that are notoriously difficult to treat. One year after they have stopped drinking, approximately one third of patients with alcoholism remain abstinent, one third have resumed drinking but not at their former level of consumption, and one third have relapsed completely. A defining problem with respect to the treatment of addiction is that we do not know how to restore the addicted brain to its former state, and many therapies — for example, methadone maintenance for opiate addiction — do not even attempt to do so. Because of the difficulty of treating addictions and . . . [Full Text of this Article]

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